Poly rc binding protein 4

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August undefined, 2024

WebPoly(rC)-binding protein 2 (PCBP2) is an RNA-binding protein that is characterized by its ability to interact with poly(C) with high affinity in a sequence-specific manner. PCBP2 … WebFind poly a binding protein and related products for scientific research at MilliporeSigma. US EN. Applications Products Services ... Synonym(s): Anti-LIP4, Anti-LYST-interacting protein, Anti-MCG10, Anti-RNA binding protein MCG10, Anti-poly(rC) binding protein 4. Compare Product No. Clonality Application Species Reactivity Citations ...

Suppression of Poly(rC)-Binding Protein 4 (PCBP4) reduced …

WebDec 8, 2024 · Orthologous to human PCBP4 (poly(rC) binding protein 4). [provided by Alliance of Genome Resources, Apr 2024] Other designations. poly(rC)-binding protein 4, … Webinternal ribosomal entry site (IRES). A cellular protein, the poly(rC) binding protein (PCBP), has been reported to interact with the CL either alone or in combination with viral protein 3CD pro. The formation of the ternary complex is essential for RNA replication and, hence, viral proliferation. PCBP also interacts with stem-loop IV of the IRES, tatta alice in borderland season 1

Multilevel regulation and molecular mechanism of poly (rC)‐binding …

WebFeb 26, 2024 · Small hairpin RNA-mediated depletion of PCBP2 dramatically decreased the viability of gastric cancer cells. Cyclin-dependent kinase 2 (CDK2) was positively regulated by PCBP2 via a direct 3′ UTR binding pathway as determined using a ribonucleoprotein immunoprecipitation assay and a biotin pulldown assay. CDK2 mediated the promoting … WebPoly (rC)-binding protein 1 (PCBP1), an RNA- or DNA-binding protein with a rela-tive molecular weight of 38 kDa, which is characterized by downregulation in many cancer … WebOct 15, 2024 · Poly (rC)-binding protein 1 (PCBP1), an RNA- or DNA-binding protein with a relative molecular weight of 38 kDa, which is characterized by downregulation in many cancer types. Numerous cases have indicated that PCBP1 could be considered as a tumor suppressor to inhibit tumorigenesis, development, and metastasis. tat talent factory

59092 - Gene ResultPcbp4 poly(rC) binding protein 4 [ (house …

WebJan 19, 2011 · Leffers et al. (1995) described the cloning and characterization of 2 cDNAs for poly (rC)-binding proteins, called PCBP1 ( 601209) and PCBP2 by them. The authors analyzed an EST database for sequences that were predicted to encode a protein with K-homologous (KH) domains. The 60- to 70-amino acid KH motifs are found in several … Webinternal ribosomal entry site (IRES). A cellular protein, the poly(rC) binding protein (PCBP), has been reported to interact with the CL either alone or in combination with viral protein … tat tact 違いWebOrthologous to several human genes including PCBP2 (poly(rC) binding protein 2). [provided by Alliance of Genome Resources, Apr 2024] pcbp2 poly(rC) binding protein 2 [ (zebrafish)] Gene ID: 321844, updated on 4-Nov-2024. Summary. Enables mRNA 3'-UTR binding activity. Predicted to be ... tat tact

"WebJul 4, 2024 · Previous studies have shown that poly (rC) binding protein 2 (PCBP2) belonging to a class of proteins that bind to poly (C) stretches of both RNA and DNA, recruits HECT-domain–containing E3 ... " - Poly rc binding protein 4

Poly rc binding protein 4

IJMS Free Full-Text Elusive Trans-Acting Factors Which Operate …

WebApr 12, 2024 · Download Citation Heme oxygenase 1 in erythropoiesis: an important regulator beyond catalyzing heme catabolism Heme oxygenase 1 (HO-1), encoded by the HMOX-1 gene, is the main heme oxygenase ... WebMar 19, 2024 · Poly(rC)-binding protein1 (PCBP1) is an RNA-binding protein that regulates mRNA stability, splicing, and translation. PCBP1 is a tumor suppressor and can inhibit the translation of several ...

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WebMar 21, 2016 · PCBP4 (Poly(RC) Binding Protein 4) is a Protein Coding gene. Diseases associated with PCBP4 include Maxillary Cancer and Jaw Cancer.Among its related … WebJul 1, 2024 · Poly(rC)-binding protein 2 (PCBP2) is a member of the poly-cytosine binding protein (PCBP) family, which has been shown to function as regulators in various diseases, including hepatitis C virus infection [2], degenerating neurons [3], acute spinal cord injury [4], and chronic obstructive pulmonary disease [5].

WebPoly(rC)-binding protein 4 is a protein that in humans is encoded by the PCBP4 gene.. This gene encodes a member of the KH domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular … WebNov 1, 2024 · Iron chaperones include the multi-functional poly(rC)-binding proteins 1–4 (PCBPs). • PCBP1/2 play roles in iron metabolism, with the roles of PCBP3/4 being less clear. • The PCBPs bind 3 iron atoms and form hetero/homo dimer complexes. • PCBPs have a subset of non-redundant functions in iron metabolism.

WebThe cellular protein poly (rC)-binding protein (PCBP) was identified as a primary candidate for regulating such a mechanism. Among the four different isoforms of PCBP in … WebFeb 26, 2024 · Poly(rC) binding protein 2 (PCBP2), a 39 kDa protein, is a member of the α-globin mRNP stability complex [7, 8]. As a generally known RNA-binding protein, PCBP2 possesses three K homology domains, which are the main RNA-recognition regions [9, 10].

WebGene ID: 128047921, updated on 28-Feb-2024. Summary Other designations. poly(rC)-binding protein 2

WebThe poly(rC)-binding proteins are a subfamily of KH-domain-containing RNA-binding proteins that bind C-rich pyrimidine tracts and play pivotal roles in a broad spectrum of … t attachmentWebNov 14, 2024 · Poly(rC)-binding proteins (PCBPs), a defined subfamily of RNA binding proteins, are characterized by their high affinity and sequence-specific interaction with … the cambridge diet reviewWebDec 8, 2024 · Orthologous to human PCBP4 (poly(rC) binding protein 4). [provided by Alliance of Genome Resources, Apr 2024] Other designations. poly(rC)-binding protein 4, alpha-CP4. GeneRIFs: Gene References Into Functions. the p53-PCBP4-ZFP871 axis represents a novel feedback loop in the p53 pathway. ... tattales tv showsWebMay 1, 2024 · Poly rC binding protein 1 (PCBP1) is a multifunctional protein that serves as a cytosolic iron chaperone, binding and transferring iron to recipient proteins in mammalian cells. Although PCBP1 ... the cambridge atlas of astronomyWebSingle-stranded nucleic acid binding protein that binds preferentially to oligo dC (PubMed:7607214, PubMed:12414943). Major cellular poly(rC)-binding protein … tattam express batemans bayWebPCBP2 knockdown promotes ferroptosis in malignant mesothelioma. PCBP2 might play important roles in central nervous system pathophysiology after spinal cord injury. that the change of poly (C)-binding proteins protein expression was associated with Schwann cell proliferation after the trauma of the peripheral nervous system. tattams freightWebHere we discuss recent and old results devoted to type I IRESes and provide evidence that Poly(rC) binding protein 2 (PCBP2), Glycyl-tRNA synthetase (GARS), and Cold Shock Domain Containing E1 (CSDE1, also known as UNR) are major regulators of type I IRES activity. the cambridge encyclopedia of the sun