WebJun 12, 2012 · However, the molecular mechanisms that underlie the early recruitment of stromal cells to sites of neoplasia remain poorly understood. Here, we demonstrate an oncogenic Kras (G12D)-dependent upregulation of GM-CSF in mouse pancreatic ductal epithelial cells (PDECs). An enhanced GM-CSF production is also observed in human … WebJan 14, 2024 · Here the authors provide a single-cell characterization of cerebrospinal fluid and blood of newly diagnosed multiple sclerosis (MS) patients, revealing altered …
Oncogenic Kras-induced GM-CSF production promotes the
WebApr 12, 2024 · Hypercalcemia–leukocytosis syndrome (HLS) as a paraneoplastic syndrome (PNS) of bladder cancers is rare, although it is documented in anaplastic thyroid, lung, and penile squamous cell carcinomas (SCCs) [1, 2].Non-schistosomiasis-associated squamous cell carcinoma (NSA-SCC) accounts for 2% of all bladder cancers in the Western world … WebJul 4, 2024 · Cerebrospinal fluid (CSF) is an ultrafiltrate of plasma contained within the ventricles of the brain and the subarachnoid spaces of the cranium and spine.[1] It performs vital functions, including providing … slay the spire best warrior cards
Cerebrospinal fluid - Wikipedia
WebBLOOD CELLS IN CSF. Increased white blood cells in the CSF may be a sign of meningitis, acute infection, beginning of a long-term (chronic) illness, tumor, abscess, or … WebJun 6, 2024 · B) CSF spindles which lack functional kinetochores. C) Interphase bead asters grow rapidly by branching nucleation, and form CPC-positive interaction zones when they meet. D) Interphase sperm asters are similar to C), but they grow asymmetrically due to CPC recruitment on the chromatin-proximal boundary (Field et al 2015). E) Cycled CSF … Webgovern spindle assembly in these two types of situations: in CSF extracts, spindle formation is predominantly initiated from asters, whereas in cycled extracts, microtubule poly-merization is initiated from chromatin (Sawin and Mitchi-son, 1991). Our data provide the first evidence for a direct involvement of the tumor suppressor APC in ... slay the spire best watcher build