국내 paclitaxel resistance a549
WebSep 7, 2024 · SOX2 regulates paclitaxel resistance of A549 non‑small cell lung cancer cells via promoting transcription of ClC‑3 . Authors Youwei Huang 1 , Xiangyu Wang 1 , … http://ir.bjmu.edu.cn/handle/400002259/135151?mode=full
국내 paclitaxel resistance a549
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WebJun 9, 2024 · Figure 3 B showed that IC50 values for paclitaxel in A549 and A549/PA cells were 1.23 ± 0.14 and 7.03 ± 0.32 μmol/L, respectively, indicating much higher values for A549/PA cells, whose resistance index (RI) was 5.02. A549/PA cells showed more powerful resistance to paclitaxel ( P < 0.05). WebMay 25, 2010 · The paclitaxel-resistant A549-Taxol cell line was established as previously reported. Briefly, the cell lines were selected to be paclitaxel resistant by continuous …
WebAug 1, 2024 · (C) A549 cells were treated with different concentration of cisplatin for 12 h, 24 h and 48 h, and western blot determined the expression level of CREB. At least three independent experiments were performed. *P < 0.05, **P < 0.01 and ***P < 0.001 compared with control. (TIF 11383 kb) 13046_2024_1299_MOESM2_ESM.tif(11M) WebIntensification of paclitaxel and 5-FU cytotoxicity in A549 and A549-PacR cells by 21α-MMD. The cytotoxicity of 21α-MMD (6.25–100 μM), paclitaxel (12.5–200 μM), and 5-FU …
WebApr 1, 2024 · All four active compounds, with IC 50 values ranging from 0.002 to 0.91 μM, had better inhibitory activities against A549/Taxol cells than paclitaxel (IC 50 = 1.80 μM). Among them, cucurbitacin E (IC 50 = 0.002 μM) is the most active. Further studies are needed to evaluate their in vivo antitumor activities and to clarify their mechanisms. WebNov 14, 2016 · Human lung cancer A549 cells, A549/PTX (paclitaxel-resistant) cells and A549/DDP (cisplatin-resistant) cells were tested. The resistance to cisplatin or paclitaxel was detected...
WebThis study aimed to investigate the effect of apatinib on the reversal of paclitaxel (PTX) resistance in A549 lung cancer cells (A549/PTX) and related mechanisms. Materials …
WebOne commonly used line is A549, an epithelial carcinoma derived from a 58 year old male patient, known to be KRAS mutant and EGFR wild type. Lung cancer is the leading cause of cancer-related deaths in the world with non-small cell lung cancer (NSCLC) making up about 85% of all lung cancer cases. marked woman 1937 full moviemarked woman 1937 bette davis humphrey bogartWebFeb 24, 2024 · Human non-small cell lung cancer cell line (A549), and paclitaxel-resistant A549 (A549/T) cell line was purchased from iCell Biosciences Inc. (Shanghai, China). Both A549/T and A549 cell lines … marked:women in the workplaceWebMay 15, 2024 · This study provides new insights into the molecular mechanism of DDP resistance in lung cancer, and downregulated miR-100–5p was proved to be involved in … naval base kitsap bangor veterinary clinicWebMar 1, 2024 · A549 cells were exposed to PTX at the concentrations of 20 nM, 40 nM, 50 nM, 70 nM, 90 nM, 100 nM for 2 weeks each concentration. 4 months were taken to construct the resistant cell line called A549-PTX. 2.2.3. CCK8 cell counting assay Cells were seeded into 96-well plates at the density of 3000 cells per well. naval base kitsap bangor post office hoursWebSilencing USP14 increased the tumor antagonistic action of DDP in A549 cisplatin-resistant (A549/DDP) cells, while USP14 overexpression decreased the antagonist effects. ... and lymphoma. 29 He et al. developed two AMs that selectively bind to two glycoproteins on the surface of a paclitaxel-resistant ovarian carcinoma cell line with high ... markee companyWebAbstract Objective To investigate the effect of the SMAC gene on paclitaxel sensitivity and cellular activity in lung adenocarcinoma cells based on the caspase-3/Bcl-2/Bax signaling pathway. Methods A paclitaxel-resistant cell line A549/Taxol was established for lung adenocarcinoma, and the cells were divided into four following groups: pcDNA-NC … naval base kitsap bremerton legal office